The Hedtrich lab’s

overall vision of the proposed research program is to develop and employ complex bioengineered human (disease) models to significantly advance our understanding of the manifestation, progression, and treatment of inflammatory and genetic diseases of human epithelia. We firmly believe that human-based models are critical closing the current translational gap in biomedical research. Hence, the Hedtrich lab’s research relies on complex human-based organ- and organ-on-chip (OoC) models. We harness these models (1) to unravel pathological mechanisms and (2) to develop and test next-generation therapies. Our interdisciplinary research requires close intersectional collaborations with clinicians, engineers, and other life sciences disciplines.

We are continuously looking for highly motivated graduate students and postdocs with interest in bioengineering of complex tissue/organ-on-chip models and gene therapy. If you are interested, please send your CV to Dr. Sarah Hedtrich.

Public Outreach

Interview with Dr. Hedtrich on the delivery of genome editing tools: https://www.advancedsciencenews.com/delivering-crispr-gene-editing-therapy-whats-holding-us-back/

Interview with Dr. Hedtrich on advances in biomedical engineering and organ-on-a-chip devices published in the UBC TREK magazine: https://trekmagazine.alumni.ubc.ca/2021/spring-2021/health-science-technology/human-chip